Eligibility: 52af484a1aea77150c3a9f454226b302 [RDF]
| Label | 52af484a1aea77150c3a9f454226b302 |
|---|---|
| Slug | 52af484a1aea77150c3a9f454226b302 |
| Criteria | DISEASE CHARACTERISTICS: - Histologically proven metastatic renal cell carcinoma not amenable to complete surgical resection and progressive despite immunotherapy - Bidimensionally evaluable clinically or radiographically - HLA 6/6 or 5/6 matched family donor available - No CNS metastases PATIENT CHARACTERISTICS: Age: - 18 to 80 Performance status: - ECOG 0 or 1 Life expectancy: - At least 3 months Hematopoietic: - Not specified Hepatic: - Bilirubin no greater than 4 mg/dL - Transaminases no greater than 3 times upper limit of normal Renal: - Creatinine no greater than 2.5 mg/dL - No malignancy-associated hypercalcemia (< 2.5 mmol/L) Cardiovascular: - Left ventricular ejection fraction greater than 40% Pulmonary: - DLCO greater than 65% of predicted Other: - Not pregnant - HIV negative - No major organ dysfunction that would preclude transplantation - No other malignancies except basal cell or squamous cell skin cancer - No psychiatric disorder or mental deficiency that would preclude study participation PRIOR CONCURRENT THERAPY: Biologic therapy - See Disease Characteristics Chemotherapy - Not specified Endocrine therapy - Not specified Radiotherapy - Not specified Surgery - Not specified Other - At least 1 month since prior treatment for renal cell carcinoma |
| Maximum age | 80 Years |
| Healthy volunteers | No |
| Study pop | |
| Minimum age | 18 Years |
| Gender | Both |
| Sampling method | |
| Provenances | http://clinicaltrials.gov/show/NCT00003553?displayxml=true |
| Similars | None |
| Interlinks | None |
